The immune system gets regulated by the endocannabinoid system [ECS]. The endocannabinoid system has –
- Cannabinoid receptors called CB1 and CB2
- AEA [endogenous cannabinoids anandamide]
- 2-AG [2-arachidonoylglycerol]
- Enzymes influencing endocannabinoids production
According to science, immune system cells include both CB1 & CB2, but the concentration of CB2 is higher than CB1.
On justcbdstore.com, you can buy different forms of cannabidiol products including CBD tinctures, edibles, pure oil, capsules, flowers, vapes, lotions, topicals, gels, soaps, etc. Let’s understand how CBD strengthens your immune system.
How does the immune system and CBD interact?
CBD or cannabidiol is a phytocannabinoid present in the cannabis Sativa plant. It is a non-psychoactive component having anti-inflammatory, anti-microbial, anti-depressant, and pain-relieving properties. CBD works with the ECS and is believed to maintain a state of homeostasis and strengthen the immune system.
TRPV2 [Transient receptor potential vanilloid 2] is a protein that allows cells to communicate with their extracellular surroundings and is crucial for a healthy immune system functioning. CBD activates the TRPV2 as well as influences other TRP channels that participate in supporting your immunity.
Proper functioning of the immune system enables your body to combat infection and diseases. A healthy immune system efficiently responds to bodily threats and inflammation is normal. On the other hand, with a poor immune system function, an inflammatory trigger is consistent and chronic.
Chronic pain is common in multiple diseases. Fortunately, hemp-based CBD can directly or indirectly help to improve your immunity.
How CBD can strengthen your immune system?
Increases natural killer cells?
According to an animal study associated with autoimmune health and CBD, it was found that hemp-based CBD oil regulated the imbalanced immune system by decreasing the activities of T-cells, B-cells, T-helper, and the T-cytotoxic lymphocyte subsets. Besides the autoimmune dome, CBD supports NK cells [natural killer cells are similar to white blood cells] and T-cells activities. The NK cells signal your body on how to respond to viruses. Vitro studies have proved CBDs effectiveness in maintaining immunity within the liver.
CBD is popular for maintaining a healthy inflammatory response. In mice that were exposed to lung irritants, CBD helped to soothe the aggravation.
In a study, CBD improved lung symptoms like decreased lung resistance [RL] and elastance [EL], myeloperoxidase activities in lung tissues, leukocyte migration in lungs, protein concentration, as well as maintaining the healthy levels of chemokines and cytokines. Thus, increase the potency of respiratory functions.
Improve gut health
A large part of your immune system is situated in the gastrointestinal tract. It includes scattered adaptive and innate effector cells along with organized lymphoid tissue. Microbiota organisms present in the gut are good as well as bad.
They play a huge role in maintaining a balanced immune system. Excess gut inflammation can cause intestinal permeability, impaired intestinal immunity, and gut microbiota dysbiosis. The only way to offset this condition is via the endocannabinoid system.
In human trials, CBD helped to decrease inflammation just like the endogenous cannabinoids in the human body. All this means you need to keep gut healthy to strengthen overall immunity.
Offers calming effect
Consistent psychological stress can trigger immunity decline. However, CBD capsules activate 5-HT1A serotonin receptors, thus relieving the stressors and regulated cerebral blood flow within the brain region that are associated with anxiety. CBD makes people calm and relaxed.